7-苯并呋喃甲酰胺, 4-氨基-5-氯-2,3-二氢-N-[1-(3-甲氧基丙基)-4-哌啶基]-
Prucalopride
CAS: 179474-81-8
Molecular Formula: C18H26ClN3O3
7-苯并呋喃甲酰胺, 4-氨基-5-氯-2,3-二氢-N-[1-(3-甲氧基丙基)-4-哌啶基]- - Names and Identifiers
| Name | Prucalopride |
| Synonyms | CS-219 R093877 Resolor R 093877 Prucalopride 4-Amino-5-chloro-2,3-dihydro-N-(1-(3-methoxypropyl)-4-piperidyl)-7-benzofurancarboxamide 4-Amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide 4-amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2,3-dihydro-1-benzofuran-7-carboxamide |
| CAS | 179474-81-8 |
| EINECS | 1312995-182-4 |
| InChI | InChI=1/C18H26ClN3O3/c1-24-9-2-6-22-7-3-12(4-8-22)21-18(23)14-11-15(19)16(20)13-5-10-25-17(13)14/h11-12H,2-10,20H2,1H3,(H,21,23) |
7-苯并呋喃甲酰胺, 4-氨基-5-氯-2,3-二氢-N-[1-(3-甲氧基丙基)-4-哌啶基]- - Physico-chemical Properties
| Molecular Formula | C18H26ClN3O3 |
| Molar Mass | 367.87 |
| Density | 1.28 |
| Melting Point | 90.7° |
| Boling Point | 481.4±45.0 °C(Predicted) |
| Flash Point | 244.9°C |
| Solubility | DMSO 60 mg/mL Water <1 mg/mL Ethanol 38 mg/mL |
| Vapor Presure | 2E-09mmHg at 25°C |
| Appearance | powder |
| Color | white to beige |
| pKa | 13.65±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.599 |
7-苯并呋喃甲酰胺, 4-氨基-5-氯-2,3-二氢-N-[1-(3-甲氧基丙基)-4-哌啶基]- - Risk and Safety
| UN IDs | UN 3077 9 / PGIII |
7-苯并呋喃甲酰胺, 4-氨基-5-氯-2,3-二氢-N-[1-(3-甲氧基丙基)-4-哌啶基]- - Introduction
Prucalopride is a selective, high affinity 5-HT receptor agonist for 5-HT4A and 5-HT4B receptor with Ki of 2.5 nM and 8 nM, respectively, exhibits >290-fold selectivity against other 5-HT receptor subtypes.
Last Update：2022-10-16 17:14:31
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View History
7-苯并呋喃甲酰胺, 4-氨基-5-氯-2,3-二氢-N-[1-(3-甲氧基丙基)-4-哌啶基]-
Ganoderma lucidum reference material
2 -(2 -(4-甲氧基苯基)乙炔基)苯甲醛
顺-13-二十二烯-1-醇
8-羟基-5-甲基-6-氧代-5,6-二氢-4H-苯并[F]咪唑并[1,5-A][1,4]二氮杂卓-3-羧酸乙酯
7-(1-乙基-5-甲基-吡唑-4-基)吡唑[1,5-A]嘧啶-2-羧酸
2-氧杂-8-氮杂螺[4.5]癸-4-醇
4-[2-(2,5-二氧代-1-苯基-吡咯烷-3-基氨基)-乙基]-苯磺酰胺
5-氨基-3-异丙基异噁唑
2-[2-羟基-3-[异丙基氨基]丙氧基]苯丙酸乙酯
Ganoderma lucidum reference material
2 -(2 -(4-甲氧基苯基)乙炔基)苯甲醛
顺-13-二十二烯-1-醇
8-羟基-5-甲基-6-氧代-5,6-二氢-4H-苯并[F]咪唑并[1,5-A][1,4]二氮杂卓-3-羧酸乙酯
7-(1-乙基-5-甲基-吡唑-4-基)吡唑[1,5-A]嘧啶-2-羧酸
2-氧杂-8-氮杂螺[4.5]癸-4-醇
4-[2-(2,5-二氧代-1-苯基-吡咯烷-3-基氨基)-乙基]-苯磺酰胺
5-氨基-3-异丙基异噁唑
2-[2-羟基-3-[异丙基氨基]丙氧基]苯丙酸乙酯